opentargets-database

Query the Open Targets Platform GraphQL API to retrieve target, disease, and drug data by identifier. The API accepts Ensembl IDs, EFO IDs, and ChEMBL IDs, returning fields like tractability, safetyLiabilities, associatedDiseases, knownDrugs, and evidence records with sources and scores for target discovery and prioritization.

Open Targets provides genetics, omics, pathways, literature, and pharmacovigilance data. You can retrieve druggability assessments, safety liabilities, genetic constraints, target-disease evidence, and known drugs to evaluate targets and identify repurposing opportunities across multiple data sources.

Yes, the Open Targets GraphQL API supports identifier-based searches using Ensembl IDs for genes, EFO IDs for diseases, and ChEMBL IDs for drugs. This enables flexible queries for target discovery, evidence gathering, and drug-target association retrieval.

Open Targets returns evidence records with associated sources and scores across genetics, omics, pathways, literature, and pharmacovigilance domains. Each record includes scoring metrics to help prioritize and validate target-disease relationships for drug discovery workflows.

Query the Open Targets GraphQL API for a disease identifier to retrieve knownDrugs records linked to disease-associated targets. This retrieves approved drugs and candidates for the disease, supporting drug repurposing and target validation strategies.