scientific-opentargets-genetics

Open Targets Platform 遺伝学スキル。Open Targets Platform GraphQL API を活用した標的-疾患アソシエーション・薬剤 エビデンス・L2G 遺伝的関連・ファーマコゲノミクス検索。 ToolUniverse 連携: opentarget。

What problem does it solve?

This skill streamlines retrieval of target-disease associations, drug evidence, and L2G mappings from the Open Targets Platform, enabling researchers to prioritize targets with genetic and pharmacological context.

Core Features & Use Cases

• Fetch target-disease associations using Ensembl IDs to obtain scores and disease details.
• Retrieve drug evidence with mechanisms of action and clinical context for prioritized targets.
• Acquire L2G variant-to-gene mappings for GWAS loci to support locus interpretation and prioritization.
• Integrate results into downstream analyses and pipelines for project planning.

Quick Start

Query the Open Targets Genetics API with an Ensembl ID to fetch target-disease associations and related drug evidence.