ena-database

Retrieve nucleotide sequences, FASTQ reads, and genome assemblies from ENA via REST APIs and FTP.

1|Updated Mar 12, 2026
One-click install
npx skills add https://github.com/yf8578/clawomics --skill ena-database-yf8578
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: ena-database
Source: https://github.com/yf8578/clawomics/tree/main/skills/ena-database
Command: npx skills add https://github.com/yf8578/clawomics --skill ena-database-yf8578

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes references (resource) components.

What problem does it solve?

This Skill provides programmatic access to the European Nucleotide Archive (ENA), enabling users to retrieve DNA/RNA sequences, raw reads, and genome assemblies for bioinformatics analyses.

Core Features & Use Cases

  • Data Retrieval: Fetch sequences, FASTQ files, and genome assemblies by accession numbers.
  • Metadata Search: Query ENA for studies, samples, and experiments based on various criteria.
  • Use Case: Retrieve all raw sequencing reads (FASTQ files) associated with a specific study accession number for downstream RNA-Seq analysis.

Quick Start

Use the ena-database skill to retrieve raw sequencing reads for accession ERR123456.

Frequently Asked Questions about ena-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve raw sequencing reads from ENA using an accession number?

To retrieve raw sequencing reads from ENA, provide a study or experiment accession number like ERR123456 to fetch associated FASTQ files. This skill queries ENA REST APIs and FTP to return raw sequencing data for downstream bioinformatics pipelines.

Can I search ENA metadata for studies and experiments programmatically?

Yes, you can search ENA metadata for studies, samples, and experiments programmatically. The skill facilitates querying the European Nucleotide Archive based on various criteria to return matching metadata records.

What types of genomic data can I access from the European Nucleotide Archive?

You can access nucleotide sequences, raw reads (FASTQ files), and genome assemblies from the European Nucleotide Archive. The skill retrieves these data types to support genomics and bioinformatics analyses.

Does this ENA data retrieval skill support bulk downloads of genome assemblies?

Yes, this ENA data retrieval skill supports bulk data downloads via FTP. It facilitates access to comprehensive public repository data, allowing you to download genome assemblies and raw reads for bioinformatics pipelines.

What is the best way to integrate ENA nucleotide sequences into a bioinformatics pipeline?

The best way to integrate ENA nucleotide sequences into a bioinformatics pipeline is using REST APIs to programmatically query and fetch data. This skill provides direct access to ENA's public repository for pipeline integration.