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ensembl-database

Queries the Ensembl genome database REST API for genes, variants, and orthologs.

8|Updated Jan 13, 2026
Search Tags:#bioinformatics#genomics#orthologs#variant analysis#ensembl#gene lookup
One-click install
npx skills add https://github.com/hxk622/TokenDance --skill ensembl-database-hxk622
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: ensembl-database
Source: https://github.com/hxk622/TokenDance/tree/main/backend/app/skills/builtin/scientific/bioinformatics/ensembl-database
Command: npx skills add https://github.com/hxk622/TokenDance --skill ensembl-database-hxk622

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires ensembl_rest, requests, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides programmatic access to the Ensembl genome database, enabling researchers to query vast amounts of genomic data for over 250 species without needing to navigate complex web interfaces or download massive datasets.

Core Features & Use Cases

  • Gene Information: Retrieve details, sequences, and annotations for genes using symbols or IDs.
  • Variant Analysis: Analyze genetic variants and predict their functional impact using VEP.
  • Comparative Genomics: Find orthologs and paralogs across different species.
  • Use Case: A researcher needs to find all human genes that are orthologous to a specific mouse gene and retrieve their DNA sequences.

Quick Start

Use the ensembl-database skill to find orthologs for the human gene BRCA2 in the mouse species.

Frequently Asked Questions about ensembl-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I query the Ensembl REST API for gene lookups across multiple species?▼

Find orthologs across 250+ species by querying the Ensembl REST API with this Skill, which retrieves comparative genomics data like orthologous genes for a specified input species.

Can I analyze genetic variants and predict functional impact using VEP?▼

Yes, you can analyze genetic variants and predict their functional impact using VEP by submitting variant data to the Ensembl REST API through this Skill's querying capabilities.

Does this Ensembl database query tool require downloading massive datasets?▼

No, this Skill provides programmatic access to the Ensembl genome database, enabling genomic data retrieval across 250+ species without downloading massive datasets or navigating complex web interfaces.

How do I retrieve DNA sequences for orthologous genes in bioinformatics pipelines?▼

Retrieve DNA sequences for orthologous genes by integrating this Skill into bioinformatics pipelines to query the Ensembl REST API for comparative genomics and sequence retrieval.

What dependencies do I need to access the Ensembl genome database via Python?▼

You need the ensembl_rest and requests Python packages to access the Ensembl genome database, facilitating gene lookups, variant analysis, and ortholog identification via HTTP requests.

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