ensembl-database

You can retrieve gene sequences using the Ensembl REST API by querying with an Ensembl ID or gene symbol to fetch corresponding DNA, transcript, or protein sequences directly from the database. The skill handles this retrieval programmatically.

Finding orthologs for a specific gene across species is done by querying the Ensembl database with a gene identifier to retrieve comparative genomics data and identify orthologous genes in other organisms.

Yes, you can analyze genetic variants and predict their effects using VEP by submitting variant data to the Ensembl REST API, which returns comprehensive variant analysis and functional predictions.

The Ensembl database REST API supports genomic data for over 250 species, allowing you to retrieve gene information, sequences, and perform comparative genomics analysis across a wide range of non-human organisms.

To look up a gene by its symbol in Ensembl, you query the REST API with the gene symbol to retrieve comprehensive gene details including its Ensembl ID, genomic location, and associated transcripts.

You need either the ensembl_rest Python package or standard HTTP requests libraries to access the Ensembl REST API, as the skill leverages these dependencies to facilitate genomic data queries.