Design and analyze proteins with ESM3/ESM C models via local or Forge inference.
npx skills add https://github.com/swaruplab/operon --skill esm-swaruplab
Please help me install this Agent Skill. Skill: esm Source: https://github.com/swaruplab/operon/tree/main/src-tauri/protocols/esm Command: npx skills add https://github.com/swaruplab/operon --skill esm-swaruplab
ESM provides state-of-the-art protein language models for understanding, generating, and designing proteins, enabling researchers to design novel proteins and analyze embeddings without deep ML expertise.
Provide a partial or masked protein sequence and run an initial generation using ESM3 with a suitable GenerationConfig to complete the design.
High-intent search queries and answers about installing and using this skill.
To design a protein with ESM3, provide a partial or masked sequence and execute an initial generation using a suitable GenerationConfig to complete the design. This enables multimodal generation across sequence, structure, and function.
Yes, you can generate protein embeddings for downstream analysis without deep ML expertise by using ESM C. It provides fast, scalable feature extraction and representations for end-to-end workflows.
You do not strictly need local model weights to run ESM3 and ESM C inference, as Forge-based access is supported. Optional model weights for esm3-sm-open-v1 or esm3-medium/large can be used for local inference.
Yes, this approach supports batch processing for large-scale protein libraries via Forge. It enables end-to-end workflows for sequence completion, structure prediction, and function conditioning across single proteins or libraries.
The best way to condition protein generation on specific functions is by using ESM3 multimodal capabilities. It enables function conditioning alongside sequence design and structure prediction to refine and explore novel proteins.
crazymsnDesign, analyze, and simulate proteins with ESM3 and ESM C models.
K-Dense-AIRetrieve AlphaFold-predicted protein structures and confidence metrics by UniProt IDs.
mkurmanGenerate protein sequences and structures using ESM3 and ESM C.
jimmc414Generate protein sequences and extract embeddings using ESM3 and ESM C.
