esm2-sequence-scoring

Community

ESM2-based sequence scoring and embeddings.

Authorzongtingwei
Version1.0.0
Installs0

System Documentation

What problem does it solve?

Sequence-level scoring and embeddings for protein sequences, enabling rapid plausibility checks and representation learning without full structure prediction.

Core Features & Use Cases

  • Compute pseudo-log-likelihood (PLL) scores for sequence plausibility.
  • Generate per-sequence embeddings for clustering, similarity search, or downstream modeling.
  • Support zero-shot variant effect insights and design screening in protein-design pipelines.

Quick Start

Run the ESM2 sequence-scoring workflow on a FASTA file to generate embeddings and PLL scores.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: esm2-sequence-scoring
Download link: https://github.com/zongtingwei/Bioclaw_Skills_Hub/archive/main.zip#esm2-sequence-scoring

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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