functional-screen-analysis
CommunityDecipher ENCODE functional genomics screens efficiently.
Authorammawla
Version1.0.0
Installs0
System Documentation
What problem does it solve?
It helps researchers analyze ENCODE's functional genomics screens, such as CRISPR, MPRA, and STARR-seq, to identify validated regulatory elements and understand their biological significance.
Core Features & Use Cases
- Identify functional regulatory elements through ENCODE screen data.
- Integrate screen results with epigenomic annotations like histone marks and chromatin accessibility.
- Use Case: A researcher investigats whether candidate enhancers are functionally validated and how they relate to disease-associated variants by overlaying CRISPR screen hits with epigenomic data.
Quick Start
Search for CRISPR screen experiments in ENCODE and analyze the significant enhancer hits by intersecting with chromatin marks and 3D contact data.
Dependency Matrix
Required Modules
None requiredComponents
scriptsreferences
💻 Claude Code Installation
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Please help me install this Skill: Name: functional-screen-analysis Download link: https://github.com/ammawla/encode-toolkit/archive/main.zip#functional-screen-analysis Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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