genomi

Analyze local genome data with natural language queries for genetic insights.

475|61|Updated May 28, 2026
One-click install
npx skills add https://github.com/exon-research/genomi --skill genomi
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: genomi
Source: https://github.com/exon-research/genomi/tree/main
Command: npx skills add https://github.com/exon-research/genomi --skill genomi

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires genomi, pandas, numpy, and includes scripts (resource) and references (resource) and assets (resource) components.

What problem does it solve?

This Skill turns your AI agent into a personal DNA expert, providing local, evidence-backed answers to questions about your genome without uploading your data to the cloud.

Core Features & Use Cases

  • Local Genome Analysis: Query your genome with natural language, and receive insights based on public genetic evidence and your genome's data.
  • Variant Interpretation: Understand the implications of specific genetic variants.
  • Pharmacogenomics: Learn how your genes affect drug metabolism and response.
  • Ancestry Insights: Explore your genetic ancestry without leaving your machine.
  • Use Case: You can ask your AI about the risk of developing a certain disease based on your DNA, or what your DNA says about your potential response to certain medications.

Quick Start

Use the genomi skill to analyze your genome and provide insights on your risk for Alzheimer's disease.

Frequently Asked Questions about genomi

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I analyze my genome locally without uploading data to the cloud?

Local genome analysis allows you to query your personal DNA dataset using natural language and receive evidence-based insights without cloud uploads. This Skill uses AI tools and local Genomi libraries to process your genome data entirely on your machine.

Can I use natural language queries to interpret genetic variants for pharmacogenomics?

Yes, you can use natural language queries for pharmacogenomics and genetic variant interpretation. The Skill processes your plain text questions locally and returns evidence-backed insights regarding how your genes affect drug metabolism and response.

Does local genome interpretation require Python and specific libraries?

Yes, local genome interpretation requires Python and a local installation of Genomi libraries. The Skill also depends on pandas and numpy to process your personal genome dataset and return evidence-based genetic insights.

What is the best way to explore genetic ancestry on my own computer?

Exploring genetic ancestry on your own computer is done by applying local data processing to your genome dataset. The Skill decodes your genome locally, enabling you to investigate ancestry insights through natural language AI queries without leaving your machine.

How does local DNA analysis work for assessing disease risk?

Local DNA analysis works by processing your personal genome dataset against public genetic evidence using AI tools. You can ask your agent about the risk of developing diseases like Alzheimer's, and it returns evidence-based insights computed locally.

What are the limitations of using local pharmacogenomics tools for medication response?

Limitations of local pharmacogenomics tools include reliance on public genetic evidence and the need for local installation of Genomi libraries. Insights are evidence-based but should be discussed with a healthcare provider before making medication decisions.

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