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gwas-database

Query the NHGRI-EBI GWAS Catalog for SNP-trait associations and study metadata.

1|Updated Mar 12, 2026
Search Tags:#bioinformatics#genetics#gwas#snp#trait association#genomic epidemiology
One-click install
npx skills add https://github.com/yf8578/clawomics --skill gwas-database-yf8578
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: gwas-database
Source: https://github.com/yf8578/clawomics/tree/main/skills/gwas-database
Command: npx skills add https://github.com/yf8578/clawomics --skill gwas-database-yf8578

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes references (resource) components.

What problem does it solve?

This Skill provides programmatic access to the NHGRI-EBI GWAS Catalog, enabling users to quickly find and analyze genetic variant associations with diseases and traits, streamlining genetic epidemiology research.

Core Features & Use Cases

  • Variant Lookup: Retrieve all known trait associations for a specific SNP (rs ID).
  • Trait Search: Find all genetic variants associated with a particular disease or trait.
  • Gene-based Search: Identify variants located within or near a specified gene.
  • Summary Statistics Access: Download or query full summary statistics for detailed analysis.
  • Use Case: A researcher wants to investigate the genetic basis of Type 2 Diabetes. They can use this Skill to find all associated SNPs, their p-values, and effect sizes, and then cross-reference these with other genomic databases.

Quick Start

Use the gwas-database skill to find all associations for the trait 'type 2 diabetes'.

Frequently Asked Questions about gwas-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I find SNP-trait associations for a specific disease in the GWAS Catalog?▼

Yes, you can retrieve all known trait associations for a specific SNP by querying the GWAS Catalog with its rs ID. The Skill enables variant lookup to access curated data on genome-wide association studies for that specific genetic marker.

Can I identify genetic variants located within or near a specified gene?▼

This Skill supports programmatic access to the GWAS Catalog via REST APIs, enabling automated data retrieval and analysis. Researchers can programmatically query variant information, study metadata, and summary statistics for genetic epidemiology workflows.

How can I access full summary statistics for detailed genetic association analysis?▼

No special dependencies are required to use this Skill for querying genomic epidemiology data. It operates independently to access the NHGRI-EBI GWAS Catalog, allowing users to retrieve variant information and study metadata without external library installations.

What is the best way to investigate the genetic basis of a complex trait like Type 2 Diabetes?▼

The best way is to query the GWAS Catalog for 'type 2 diabetes' to find all associated SNPs, their p-values, and effect sizes. You can then cross-reference these variant associations with other genomic databases for comprehensive research.

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