One-click install
npx skills add https://github.com/silverstein/claude-scientific-skills-desktop --skill histolab-silverstein
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: histolab
Source: https://github.com/silverstein/claude-scientific-skills-desktop/tree/main/corpus/histolab
Command: npx skills add https://github.com/silverstein/claude-scientific-skills-desktop --skill histolab-silverstein

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes references (resource) components.

What problem does it solve?

Histolab streamlines digital pathology workflows by helping you preprocess whole slide images (WSI) into useful tissue regions and tile datasets without manual, error-prone steps.

Core Features & Use Cases

  • Whole-slide management: Load WSIs, inspect magnification and pyramid levels, and create thumbnails and regions for downstream analysis.
  • Tissue detection & segmentation: Generate binary tissue masks (including largest-tissue bounding-box masking) to filter background, artifacts, and non-informative areas.
  • Tile extraction for computational pathology: Sample tiles using random, grid, or score-based strategies, optionally outputting reports (e.g., nuclei-density scoring) for dataset curation.

Quick Start

Use the histolab skill to extract tissue-focused tiles from a WSI by loading a slide, previewing candidate tile locations, and then running a tiler with a tissue mask for your desired tile size.

Frequently Asked Questions about histolab

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I extract tiles from whole slide images for deep learning datasets?

To extract tiles from whole slide images, load the WSI, generate a binary tissue mask to filter background, and apply a tiler to sample tissue-focused tiles using random, grid, or score-based strategies.

What is tissue segmentation in whole slide images and when do I need it?

Tissue segmentation in whole slide images generates binary tissue masks to isolate informative regions, filtering out background and artifacts, which is needed before tiling to ensure computational pathology datasets contain only relevant tissue.

Can I use score-based sampling for tile extraction in computational pathology?

Yes, score-based sampling is supported for tile extraction in computational pathology, allowing you to curate datasets by generating tiles with optional reports like nuclei-density scoring to select the most informative tissue regions.

How do I filter non-informative areas when preprocessing H&E slides?

To filter non-informative areas when preprocessing H&E slides, generate a binary tissue mask, optionally using the largest-tissue bounding-box masking feature to exclude background and artifacts from downstream tile extraction.

Does whole slide image preprocessing work with specific pyramid levels and magnifications?

Whole slide image preprocessing supports inspecting magnification and pyramid levels, allowing you to configure the tiler to extract tissue-focused tiles from the desired WSI pyramid level for computational pathology workflows.

What is the best way to create a tissue mask for whole slide images?

The best way to create a tissue mask for whole slide images is to generate a binary mask that isolates tissue regions, optionally applying largest-component bounding box masking to focus on the primary tissue area and exclude artifacts.