hlatyping

Run the nf-core/hlatyping workflow on samplesheet-based DNA or RNA sequencing data.

1|Updated Jun 19, 2026
One-click install
npx skills add https://github.com/danilomonge/nf-claw --skill hlatyping
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: hlatyping
Source: https://github.com/danilomonge/nf-claw/tree/main/pipelines/hlatyping
Command: npx skills add https://github.com/danilomonge/nf-claw --skill hlatyping

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

This Skill removes uncertainty from running the nf-core/hlatyping workflow by exposing the exact inputs, version-specific parameters, and execution details needed to launch HLA typing correctly.

Core Features & Use Cases

  • Samplesheet-driven runs for sequencing datasets, including DNA and RNA inputs.
  • Release-aware guidance for required parameters, allowed values, and pipeline version selection.
  • Reproducible execution with clear output locations and provenance-friendly runtime behavior.
  • Use case: process a cohort of patient sequencing samples and generate standardized HLA typing calls for downstream interpretation.

Quick Start

Ask the assistant to run hlatyping on your samplesheet, choose the desired Nextflow profile and output directory, and produce a provenance-backed HLA typing result.

Frequently Asked Questions about hlatyping

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I run HLA typing on sequencing reads using a samplesheet?

You can run HLA typing by providing a schema-checked samplesheet to the nf-core/hlatyping workflow, explicitly selecting Nextflow profiles, pipeline release versions, and validated output paths to ensure reproducible execution.

What is the nf-core hlatyping workflow used for in bioinformatics?

The nf-core hlatyping workflow produces HLA typing results from sequencing data. It supports samplesheet-driven DNA or RNA analysis, applying release-specific parameters to generate calls for downstream interpretation.

Can I use Nextflow profiles to control HLA typing pipeline execution?

Yes, Nextflow profiles must be selected explicitly when launching the HLA typing workflow. This controls runtime execution, manages provenance capture, and ensures reproducible behavior across different computing environments.

Do I need to specify a pipeline release version for nf-core hlatyping?

Yes, a release-specific pipeline version must be explicitly selected when running the HLA typing workflow. This enforces release-aware parameter validation and ensures reproducible execution of the sequencing analysis.

Does the hlatyping workflow support both DNA and RNA sequencing inputs?

Yes, the hlatyping workflow supports both DNA and RNA sequencing inputs through samplesheet-driven analysis. It requires validated input paths and schema-checked parameters to process patient cohorts and generate HLA typing calls.