hypogenic

Generates and tests hypotheses from tabular and literature data using LLMs via CLI or Python API.

4|1|Updated Jun 18, 2025
One-click install
npx skills add https://github.com/HolobiomicsLab/Toolomics --skill hypogenic-holobiomicslab
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: hypogenic
Source: https://github.com/HolobiomicsLab/Toolomics/tree/main/mcp_host/skills/scientific-skills/scientific-skills/hypogenic
Command: npx skills add https://github.com/HolobiomicsLab/Toolomics --skill hypogenic-holobiomicslab

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes references (resource) components.

What problem does it solve?

Hypogenic automates hypothesis generation and testing using large language models to accelerate scientific discovery by combining data-driven insights with literature integration across domains like deception detection, content analysis, and more.

Core Features & Use Cases

  • Data-driven HypoGeniC: generate testable hypotheses from tabular data to accelerate discovery.
  • Literature integration (HypoRefine/Union): synergize papers with data for robust hypothesis banks and validation.
  • CLI and Python API workflows: end-to-end capabilities for generation, inference, and evaluation with reproducibility.

Quick Start

Install the hypogenic package and run a basic hypothesis generation and inference workflow with the CLI or Python API.

Frequently Asked Questions about hypogenic

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I automate hypothesis generation from tabular data using LLMs?

To automate hypothesis generation from tabular data, use a workflow like HypoGeniC to process datasets and generate testable hypotheses. This approach accelerates scientific discovery by combining data-driven insights with literature integration.

What is literature-informed hypothesis testing in data-driven discovery?

Literature-informed hypothesis testing synergizes research papers with data analysis to create robust hypothesis banks. This integration validates hypotheses against existing literature, ensuring data-driven discovery is grounded in prior scientific knowledge.

Can I use Python API for programmatic control of the hypothesis generation pipeline?

Yes, you can use a Python API for programmatic control of the hypothesis generation pipeline. This allows end-to-end capabilities for generation, inference, and evaluation with reproducibility within your research workflow.

Does GROBID work with literature processing for research workflow integration?

Yes, GROBID works with optional literature processing to extract and parse information from research papers. This integration supports the literature-informed analysis needed for refining hypotheses during the discovery process.

What's the best way to combine literature and data for hypothesis validation?

The best way to combine literature and data for hypothesis validation is using methods like HypoRefine or Union. These approaches synergize papers with tabular data to build robust hypothesis banks and accelerate scientific discovery.

When should I not use LLM-based hypothesis generation for research?

You should avoid LLM-based hypothesis generation when working without structured tabular data or relevant literature. The workflow requires data-driven inputs and configuration-driven pipelines to produce valid, testable hypotheses across domains.