Access JASPAR to retrieve transcription factor binding profiles and scan DNA sequences.
npx skills add https://github.com/yf8578/clawomics --skill jaspar-database-yf8578
Please help me install this Agent Skill. Skill: jaspar-database Source: https://github.com/yf8578/clawomics/tree/main/skills/jaspar-database Command: npx skills add https://github.com/yf8578/clawomics --skill jaspar-database-yf8578
This Skill provides programmatic access to the JASPAR database, enabling users to find and analyze transcription factor binding site (TFBS) profiles, which are crucial for understanding gene regulation.
Use the jaspar-database skill to search for human CTCF binding profiles.
High-intent search queries and answers about installing and using this skill.
To retrieve transcription factor binding profiles from the JASPAR database, use this Skill to search for specific matrices by TF name, species, or class. It provides programmatic access to retrieve detailed Position Frequency Matrices (PFMs) for regulatory genomics research.
Yes, you can scan DNA sequences for potential transcription factor binding sites using PWM data. The Skill converts Position Frequency Matrices into Position Weight Matrices (PWMs) and scans input sequences to identify matching regulatory motifs.
The best way to analyze the impact of genetic variants on transcription factor binding motifs is to use this Skill's variant impact analysis functionality. It assesses how sequence changes affect TF binding by leveraging JASPAR PFM and PWM scanning capabilities.
Yes, this JASPAR query tool requires Python dependencies like requests and numpy to function. These libraries support the programmatic HTTP access to the database and the numerical calculations needed for PWM data processing.
To find all known binding motifs for a specific transcription factor in humans, use this Skill to search the JASPAR database by TF name and filter by the human species. This retrieves the relevant Position Frequency Matrices for your target regulatory genomics analysis.
sagunkayasthaQuery JASPAR for transcription factor binding profiles and scan DNA sequences.
JosephWoodallRetrieve and apply JASPAR transcription factor binding profiles to scan DNA sequences for regulatory motifs.
ammawlaAnalyze ENCODE CRISPR, MPRA, and STARR-seq screens to validate regulatory elements.
biomaps-infraQuery JASPAR for transcription factor binding site profiles and matrices.
