monarch-database

To map cross-species disease-gene-phenotype associations, query the Monarch Initiative knowledge graph to retrieve integrated data across OMIM, ORPHANET, HPO, and model organism databases for rare disease gene discovery.

Finding HPO and MONDO terms for rare disease gene discovery involves performing ontology lookups via the Monarch API v3 to match specific phenotypes and diseases to their corresponding gene associations.

Yes, you can retrieve orthology data across model organism databases by querying the Monarch Initiative knowledge graph, which supports cross-species disease modeling and integrates literature cross-referencing for rare diseases.

Yes, the Monarch API supports phenotype-to-gene mapping by providing integrated cross-ontology querying that links phenotype annotations directly to gene associations found within OMIM and ORPHANET records.