neoantigen-vaccine-design
OfficialEnd-to-end neoantigen design for animals
AuthorOpenVet-Projects
Version1.0.0
Installs0
System Documentation
What problem does it solve?
Guides a complete computational workflow to design personalized neoantigen cancer vaccines for veterinary patients, integrating tumor/normal sequencing, somatic variant calling, DLA/MHC typing, neoantigen prediction, and candidate selection.
Core Features & Use Cases
- End-to-end pipeline from tumor-normal sequencing through neoantigen prioritization and vaccine design.
- Veterinary-focused MHC typing with DLA support and cross-species adaptation of pvactools/NetMHCpan for canine, feline, and equine species.
- Vaccine design guidance for mRNA or peptide-based constructs, with veterinary immunology considerations and ethical safeguards.
Quick Start
Provide tumor/normal sequencing data and run the full pipeline from somatic variant calling through neoantigen prioritization to vaccine design.
Dependency Matrix
Required Modules
None requiredComponents
Standard package💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: neoantigen-vaccine-design Download link: https://github.com/OpenVet-Projects/VetClaw/archive/main.zip#neoantigen-vaccine-design Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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