precision-medicine-mrna-design

Official

Personalized veterinary cancer care with mRNA

AuthorOpenVet-Projects
Version1.0.0
Installs0

System Documentation

What problem does it solve?

This skill provides a comprehensive framework to connect canine and feline tumor genomics to personalized mRNA vaccine design, pharmacogenomics, and companion diagnostics for veterinary oncology.

Core Features & Use Cases

  • End-to-end workflow: tumor sequencing, neoantigen prediction, mRNA construct design, lipid nanoparticle formulation, and immune monitoring.
  • Pharmacogenomics integration: dosing optimization based on germline variants to reduce toxicity and improve efficacy in veterinary patients.
  • Companion diagnostics integration: biomarker-driven therapy selection to enable precision veterinary oncology.
  • Real-world example: Rosie-like case where a canine mast cell tumor is targeted with a personalized mRNA vaccine alongside standard therapy.

Quick Start

Generate a personalized mRNA vaccine design for a veterinary cancer case using a provided tumor genome and pharmacogenomic profile.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: precision-medicine-mrna-design
Download link: https://github.com/OpenVet-Projects/VetClaw/archive/main.zip#precision-medicine-mrna-design

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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