opentargets-database

Use the Open Targets Platform GraphQL API at api.platform.opentargets.org/api/v4/graphql to query target-disease associations and retrieve evidence scores. The Python helpers in scripts/query_opentargets.py perform common queries to fetch target annotations and disease associations without authentication.

Open Targets target discovery aggregates genetics, omics, and pharmacology datasets to calculate evidence scores for drug target prioritization. You retrieve comprehensive target information including tractability, safety liabilities, and genetic constraints by querying the platform's GraphQL endpoint.

Yes, you can find known drugs for diseases and inspect drug-indication relationships and mechanisms using the Open Targets GraphQL API. Query the platform to retrieve drug target data, known drug annotations, and target-disease associations for drug repurposing planning.

No authentication is required to query the Open Targets Platform GraphQL API for drug targeting data. You only need the requests Python dependency and the included query helpers in scripts/query_opentargets.py to retrieve target information and disease associations.

Query the Open Targets GraphQL API to retrieve comprehensive target information including tractability, safety liabilities, and genetic constraints. Use the Python helpers to perform these queries and build end-to-end workflows for target prioritization and safety assessment.

The Open Targets GraphQL API requires the requests Python dependency and relies on the platform's available datasets spanning genetics, omics, and pharmacology. Target discovery is constrained to the evidence scores and annotations currently provided by the Open Targets Platform without additional data integration.