opentargets-database

Query the Open Targets GraphQL API for target-disease associations and known drugs.

48|6|Updated Mar 9, 2026
One-click install
npx skills add https://github.com/qinyan-ai/qinyan-academic-skills --skill opentargets-database-qinyan-ai
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: opentargets-database
Source: https://github.com/qinyan-ai/qinyan-academic-skills/tree/main/skills/12-%E7%A7%91%E5%AD%A6%E6%95%B0%E6%8D%AE%E5%BA%93/opentargets-database
Command: npx skills add https://github.com/qinyan-ai/qinyan-academic-skills --skill opentargets-database-qinyan-ai

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, and includes scripts (resource) and references (resource) components.

What problem does it solve?

Open Targets Platform provides programmatic access to integrate target-disease evidence, enabling systematic target discovery, disease mapping, and drug repurposing analyses.

Core Features & Use Cases

  • Search for targets, diseases, and drugs using a GraphQL-based API.
  • Retrieve target information, disease details, associated evidence, and known drugs for diseases.
  • Build end-to-end workflows for target discovery, target validation, and drug repurposing analyses with structured queries.

Quick Start

Query the Open Targets GraphQL API to fetch target-disease associations for a specified gene or retrieve known drugs for a disease.

Frequently Asked Questions about opentargets-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I query the Open Targets API for target-disease associations?

Query the Open Targets GraphQL API to identify target-disease associations by searching for specified genes and retrieving linked evidence, disease details, and known drugs using structured requests and pagination support.

Can I retrieve known drugs for a specific disease using bioinformatics APIs?

Yes, you can retrieve known drugs for a disease by querying the Open Targets API, which fetches detailed pharmacological associations and disease mapping information through structured GraphQL queries and pagination support.

What is the best way to integrate genetics and pharmacology evidence for drug repurposing?

Integrate genetics and pharmacology evidence for drug repurposing by querying the Open Targets API, which applies structured GraphQL queries to systematically map target-disease links and fetch associated evidence across multiple data sources.

Does this target discovery workflow support pagination for fetching large evidence datasets?

Yes, target discovery workflows support pagination by utilizing built-in helper functions to fetch large volumes of evidence, target details, and known drugs from the Open Targets GraphQL endpoint without hitting data retrieval limits.

Do I need GraphQL endpoint access to perform disease mapping and target validation analyses?

Yes, you need access to the Open Targets GraphQL endpoint to perform disease mapping and target validation, as the workflow relies on structured GraphQL queries to search and retrieve therapeutic targets and associated evidence.

How does target discovery work when searching across literature and pharmacology data?

Target discovery works by querying the Open Targets API to search across genetics, pharmacology, and literature data, systematically retrieving target information and associated disease evidence to build end-to-end validation workflows.