opentrons-integration

Create and validate Opentrons Protocol API v2 protocols for OT-2 and Flex robots.

1|Updated Mar 11, 2026
One-click install
npx skills add https://github.com/SciMate-AI/scicli --skill opentrons-integration-scimate-ai
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: opentrons-integration
Source: https://github.com/SciMate-AI/scicli/tree/main/internal/skills/bundled/claude-scientific-skills/skills/opentrons-integration
Command: npx skills add https://github.com/SciMate-AI/scicli --skill opentrons-integration-scimate-ai

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires opentrons, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This skill enables researchers and engineers to author, test, and iterate Opentrons Protocol API v2 protocols for OT-2 and Flex robots using ready-made templates and official API tooling.

Core Features & Use Cases

  • Template-driven protocol scaffolding for common workflows (basic transfers, PCR setup, serial dilutions).
  • Seamless module and labware integration via the Opentrons Protocol API v2, enabling rapid prototyping and simulation.
  • Real-world use cases include designing automated pipetting workflows for assays, PCR setups, and dilution series with reusable templates.

Quick Start

Create a protocol from the bundled templates in scripts/ and test it in simulation before execution.

Frequently Asked Questions about opentrons-integration

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I create an Opentrons protocol for PCR setup and serial dilutions?

You can create an Opentrons protocol for PCR setup and serial dilutions using ready-made templates bundled in the scripts/ directory. These templates provide scaffolded code that automates liquid-handling workflows via the Protocol API v2.

What is the best way to automate liquid-handling workflows for OT-2 and Flex robots?

Automating liquid-handling workflows for OT-2 and Flex robots is best handled using the Opentrons Protocol API v2. This skill provides official templates for basic transfers, PCR setups, and dilution series to streamline robotic pipetting.

Does this Opentrons API integration support custom labware and pipette modules?

Yes, the Opentrons API integration supports loading custom labware, pipettes, and modules via the Protocol API v2. This enables rapid prototyping and simulation of complex automated lab workflows before physical execution.

Can I test and simulate Opentrons protocols before running them on the robot?

Yes, you can test and simulate Opentrons protocols before execution. The skill enables researchers to author, iterate, and validate Protocol API v2 scripts in simulation, ensuring the automated pipetting workflow is correct.

Do I need Python to use the Opentrons Protocol API v2 templates?

Yes, you need Python to use the Opentrons Protocol API v2 templates. The skill requires access to the Opentrons API v2, Python, and the protocol templates located in scripts/ to automate lab workflows.

Why use template-driven scaffolding for Opentrons lab automation?

Template-driven scaffolding for Opentrons lab automation provides reusable structures for common assays and dilution series. This approach accelerates protocol development by offering pre-built code for rapid prototyping and simulation.