phylogetics

Construct and analyze phylogenetic trees from sequence data using MAFFT, IQ-TREE 2, FastTree, and ETE3.

321|26|Updated Mar 10, 2026
One-click install
npx skills add https://github.com/mkurman/tamux --skill phylogetics
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: phylogetics
Source: https://github.com/mkurman/tamux/tree/main/skills/scientific-skills/phylogenetics
Command: npx skills add https://github.com/mkurman/tamux --skill phylogetics

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires mafft, iqtree2, and includes scripts (resource) and references (resource) components.

What problem does it solve?

Reconstruct evolutionary relationships and analyze sequence data by building and interpreting phylogenetic trees.

Core Features & Use Cases

  • MAFFT for multiple sequence alignment; IQ-TREE 2 for maximum likelihood tree inference; FastTree for large datasets; ETE3/FigTree for visualization.
  • Applicable to microbial genomics, viral phylodynamics, protein family analyses, and molecular clock studies.
  • Use cases include tracing outbreak lineages, comparing gene families, and dating divergence events.

Quick Start

Run the phylogenetic pipeline on your unaligned sequences to generate a rooted, visualizable tree.

Frequently Asked Questions about phylogetics

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I build a phylogenetic tree from unaligned sequences?

You can construct a phylogenetic tree by running this pipeline on unaligned sequences; it handles MAFFT alignment, IQ-TREE 2 inference, and ETE3 visualization automatically to produce a rooted, visualizable tree.

What is the best way to trace viral outbreak lineages using sequence data?

The best way to trace viral outbreak lineages is through phylogenetic tree construction, which infers evolutionary relationships from sequence data and supports viral phylodynamics and molecular clock studies.

Does this phylogenetic pipeline work with large datasets?

Yes, this phylogenetic pipeline supports large datasets by utilizing FastTree, which is specifically included alongside IQ-TREE 2 for efficient maximum likelihood tree inference on extensive sequence collections.

Do I need to install IQ-TREE 2 and MAFFT before constructing evolutionary trees?

Yes, you must install MAFFT and IQ-TREE 2 as dependencies before constructing evolutionary trees; installation instructions for these required tools are included in the skill description.

How do I visualize a phylogenetic tree after maximum likelihood inference?

You can visualize a phylogenetic tree after maximum likelihood inference using the ETE3 Python library and FigTree, which are integrated into the pipeline to render and interpret the inferred evolutionary relationships.

Can I use this for protein family analysis and dating divergence events?

Yes, you can use this pipeline for protein family analysis and dating divergence events, as it supports molecular clock studies and comparing gene families through phylogenetic tree construction.