query-geo

Search GEO databases for gene expression datasets by keywords and accession types.

30|2|Updated Mar 13, 2026
One-click install
npx skills add https://github.com/IDEA-XL/MolClaw --skill query-geo-idea-xl
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: query-geo
Source: https://github.com/IDEA-XL/MolClaw/tree/main/.claude/skills/query-geo
Command: npx skills add https://github.com/IDEA-XL/MolClaw --skill query-geo-idea-xl

SYSTEM DOCUMENTATION & REQUIREMENTS

## What problem does it solve? Researchers need to locate useful public gene expression datasets in NCBI GEO quickly, without sifting through irrelevant results, to support downstream analyses.

## Core Features & Use Cases

  • Keyword-based searches to discover GEO series (GSE) and platform data (GPL) by disease term, tissue, or experiment type.
  • Summaries and metadata retrieval to compare dataset size, organism, platform, and sample count at a glance.
  • Use Case: A user investigates a cancer type and wants RNA-seq or microarray GEO datasets with associated metadata for meta-analysis.

Quick Start

Run a keyword search like "breast cancer RNA-seq" to locate matching GEO datasets and fetch summaries.

Frequently Asked Questions about query-geo

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I find public gene expression datasets in NCBI GEO by keyword?

You can find public gene expression datasets in NCBI GEO by running keyword searches for disease terms, tissues, or experiment types. The tool queries Entrez and GEO APIs to retrieve matching dataset summaries and metadata for quick review.

What metadata is retrieved when searching for GEO series and platform data?

Searching for GEO series and platform data retrieves summaries that include dataset size, organism, platform, and sample count. This metadata allows researchers to compare RNA-seq and microarray studies at a glance for meta-analysis.

Can I look up specific GEO accession types like GSE and GDS?

Yes, you can perform accession lookups for specific types like GSE and GDS. The tool uses Entrez and GEO APIs to fetch dataset summaries and metadata directly associated with those accession identifiers.

Does this work for both RNA-seq and microarray datasets in GEO?

Yes, this works for both RNA-seq and microarray datasets in GEO. Keyword searches will discover GEO series across these experiment types, fetching associated metadata to support downstream research inquiries.

What is the best way to locate GEO datasets for a specific disease or tissue inquiry?

The best way to locate GEO datasets for a disease or tissue inquiry is to run a keyword search like "breast cancer RNA-seq." This queries GEO databases and returns matching public gene expression datasets with robust parsing.

Why should I use a dedicated search tool instead of manually filtering NCBI GEO results?

Using a dedicated search tool prevents sifting through irrelevant results when locating public gene expression datasets. It parses Entrez and GEO APIs to retrieve clear dataset summaries, saving time during meta-analysis preparation.