query-geo

Search GEO databases for gene expression datasets by keyword, organism, and accession type.

401|53|Updated Feb 26, 2026
One-click install
npx skills add https://github.com/Runchuan-BU/BioClaw --skill query-geo
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: query-geo
Source: https://github.com/Runchuan-BU/BioClaw/tree/main/.claude/skills/query-geo
Command: npx skills add https://github.com/Runchuan-BU/BioClaw --skill query-geo

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Researchers need to discover public gene expression datasets in GEO for RNA-seq and microarray studies, but manually searching and compiling metadata is time-consuming and error-prone.

Core Features & Use Cases

  • Search GEO by keywords, organism, and accession type (GSE/GDS) to discover relevant datasets.
  • Retrieve dataset summaries including title, accession, platform, sample count, and a concise description.
  • Explore Series (GSE) entries and view direct URLs for quick download or downstream analysis.
  • Use case: a researcher investigates a disease and wants public RNA-seq or microarray data for meta-analysis.

Quick Start

Ask me to search GEO for a keyword and I will return matching GSE/GDS entries with summaries.

Frequently Asked Questions about query-geo

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I search GEO datasets for specific RNA-seq or microarray keywords?

Search GEO by keyword, organism, and accession type like GSE or GDS to find public gene expression datasets, returning structured results with accession IDs, titles, platforms, sample counts, and concise descriptions.

Can I retrieve GSE series entries and direct download links for microarray data?

Yes, you can retrieve GSE Series entries for microarray data, which include direct URLs for quick download and downstream analysis. The query returns accession, title, platform, sample count, and a concise description.

What is the best way to find public gene expression datasets for a specific disease meta-analysis?

Apply GEO queries to disease-oriented searches to discover public RNA-seq and microarray datasets, satisfying programmatic search requirements by parsing terms and presenting ready-to-use summaries with sample counts and platforms.

Does querying GEO return sample counts and platform details for RNA-seq datasets?

Querying GEO returns structured results for RNA-seq datasets that include the accession, title, platform, sample count, and a concise summary. This metadata supports quick evaluation before downloading.

How do I compile GDS and GSE metadata without manually searching GEO?

Use programmatic GEO queries to handle search terms, parse results, and present ready-to-use summaries for GDS and GSE entries, avoiding manual searching errors and returning structured metadata including sample counts and direct URLs.

When should I use GSE versus GDS accession types to explore GEO datasets?

Use GSE to explore Series entries with direct URLs for downstream analysis, or GDS to find curated GEO dataset profiles. Searching by accession type filters results to match specific RNA-seq or microarray research requirements.