query-interpro

Query the InterPro REST API for protein domains, families, and functional sites.

1|Updated Mar 12, 2026
One-click install
npx skills add https://github.com/yf8578/clawomics --skill query-interpro-yf8578
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: query-interpro
Source: https://github.com/yf8578/clawomics/tree/main/skills/query-interpro
Command: npx skills add https://github.com/yf8578/clawomics --skill query-interpro-yf8578

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill helps you understand the functional components of proteins by querying the InterPro database for domains, families, and motifs.

Core Features & Use Cases

  • Protein Domain Analysis: Identify and retrieve information about protein domains, families, and functional sites for a given protein (e.g., UniProt ID).
  • Domain Architecture: Visualize the arrangement of domains within a protein sequence.
  • Use Case: When analyzing a newly discovered protein, use this Skill to quickly determine its known functional domains and potential roles.

Quick Start

Query InterPro for the protein domains associated with UniProt ID P04637.

Frequently Asked Questions about query-interpro

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I find protein domains and families for a specific UniProt ID?

You can find protein domains and families by querying the InterPro REST API with a specific UniProt ID. This returns structured JSON responses detailing the protein's known functional components and domain architecture.

What is the InterPro database used for in protein analysis?

The InterPro database is used in protein analysis to classify sequences into families and identify domains and motifs. It helps researchers uncover functional insights and determine the potential roles of newly discovered proteins.

Can I search InterPro entries by keyword instead of a UniProt ID?

Yes, you can search InterPro entries by keywords to find relevant protein families, domains, and functional sites. The Skill queries the InterPro REST API to retrieve matching entries and returns the results in a structured JSON format.

Do I need the requests library to retrieve protein domain architecture from InterPro?

Yes, you need the requests library installed in your Python environment to retrieve protein domain architecture. It is required to handle the API interaction with the InterPro REST service and return structured JSON responses.

How do I visualize the arrangement of domains within a protein sequence?

To visualize the arrangement of domains within a protein sequence, retrieve the domain architecture data by querying InterPro with a UniProt ID. The API provides the structural layout of domains, families, and functional sites across the sequence.