Queries Reactome pathways and reactions via ContentService and AnalysisService APIs.
npx skills add https://github.com/Runchuan-BU/BioClaw --skill query-reactome
Please help me install this Agent Skill. Skill: query-reactome Source: https://github.com/Runchuan-BU/BioClaw/tree/main/.claude/skills/query-reactome Command: npx skills add https://github.com/Runchuan-BU/BioClaw --skill query-reactome
Enable researchers to quickly find, inspect, and analyze biological pathways and individual reactions without manually navigating Reactome APIs or parsing heterogeneous results.
Run a pathway enrichment on the gene list BRCA1, BRCA2, TP53, ATM, CHEK2 and return the top Reactome pathways with p-values and found gene counts.
High-intent search queries and answers about installing and using this skill.
Pathway enrichment submits a gene list to the Reactome AnalysisService API to identify enriched biological pathways, returning associated statistics like p-values and found gene counts for downstream interpretation.
Retrieving pathway details uses the Reactome ContentService API to fetch pathway metadata, component proteins and genes, and reaction summaries directly from a provided pathway ID.
Yes, keyword pathway search accepts natural-language queries to find matching biological pathway records and their corresponding Reactome IDs for human and model organisms.
Submitting gene symbols like BRCA1 and TP53 to the AnalysisService automatically identifies top Reactome pathways, eliminating the need to manually navigate Reactome APIs or parse heterogeneous results.
Pathway enrichment and retrieval support both human and model organisms, accepting standard gene symbols, pathway IDs, or search keywords as inputs for biological pathway analysis.
Reactome pathway analysis requires HTTP access to communicate with the ContentService and AnalysisService API endpoints for fetching diagrams, listing participants, and running gene list enrichment.
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