query-reactome

Query Reactome ContentService and AnalysisService APIs for pathways, reactions, and enrichment results.

30|2|Updated Mar 13, 2026
One-click install
npx skills add https://github.com/IDEA-XL/MolClaw --skill query-reactome-idea-xl
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: query-reactome
Source: https://github.com/IDEA-XL/MolClaw/tree/main/.claude/skills/query-reactome
Command: npx skills add https://github.com/IDEA-XL/MolClaw --skill query-reactome-idea-xl

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

This skill helps researchers quickly access Reactome data to discover biological pathways, reactions, and enrichment insights without manual API calls.

Core Features & Use Cases

  • Search pathways by keyword to find relevant pathways.
  • Retrieve detailed pathway data, including participants.
  • Perform gene list enrichment analyses.
  • Use cases include pathway diagrams, reaction details, and upstream/downstream analyses.

Quick Start

Ask me to find pathways for a keyword or gene list and I will query Reactome and return the results.

Frequently Asked Questions about query-reactome

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I find biological pathways using a gene list?

To find biological pathways using a gene list, you perform enrichment analysis to retrieve matching pathways and reactions. Submitting your gene list returns enrichment results and relevant pathway diagrams across species.

What is Reactome pathway search and how does it work?

Reactome pathway search queries the ContentService API to retrieve signaling cascades, reactions, and participant details. It works by matching user-provided keywords against a database of biological pathways and reaction details.

Can I retrieve detailed participants and reactions for a specific pathway?

Yes, you can retrieve detailed participants and reactions for a specific pathway. Querying Reactome pathway details returns comprehensive data on signaling cascades and participating molecules for the requested biological pathway.

Does Reactome enrichment analysis support multiple species?

Yes, Reactome enrichment analysis supports querying pathway and reaction details across species. You can analyze gene lists and retrieve relevant signaling cascades for various organisms without manual API calls.

What's the best way to search for signaling cascades by keyword?

The best way to search for signaling cascades by keyword is to submit the term directly to the Reactome ContentService API. This retrieves relevant pathways, reaction details, and associated biological pathway diagrams.