ribo-seq

What problem does it solve?

Automates end-to-end ribosome profiling analysis from raw reads to translation efficiency insights, enabling researchers to extract meaningful translation signals with minimal manual setup.

Core Features & Use Cases

• P-site aware preprocessing and read offset estimation
• Periodicity validation, frame enrichment checks, and ORF discovery
• Translation efficiency estimation and transcript-level reporting
• Use Case: compare ribosome occupancy with RNA-seq to infer translational regulation across conditions

Quick Start

Provide ribo-seq reads (and optional matched RNA-seq) along with transcript annotations to run the workflow.