scientific-civic-evidence

What problem does it solve?

Enables researchers to efficiently retrieve and interpret clinical evidence for cancer-related variants from the CIViC REST API, aggregating evidence items, gene summaries, molecular profiles, and assertions for downstream analysis.

Core Features & Use Cases

• CIViC REST API integration for variant search, gene summaries, evidence extraction, and assertion retrieval.
• Pipeline-ready outputs: CSV/structured data for integration into precision oncology workflows.
• Use Case: when evaluating a specific cancer variant to gather clinical interpretation, evidence items, and guideline assertions.

Quick Start

Run the CIViC pipeline by calling civic_pipeline with a gene name and optional variant to fetch summaries, variants, evidence, and assertions into an organized output directory.