scientific-clingen-curation

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ClinGen data curation for gene-disease evidence.

Authornahisaho
Version1.0.0
Installs0

System Documentation

What problem does it solve?

ClinGen clinical genome resource curation helps researchers and clinicians rapidly assess gene-disease evidence, enabling consistent, scalable data curation.

Core Features & Use Cases

  • Gene-disease validity evaluation via ClinGen API for evidence classification.
  • Dosage sensitivity assessment (haploinsufficiency/triplosensitivity) to inform clinical interpretations.
  • ClinGen actionability scoring and integrated curation pipeline for clinical decision support.
  • ToolUniverse integration: ClinGen data accessible through the clingen resource.

Quick Start

Run ClinGen pipeline to fetch gene-disease validity, dosage sensitivity, and actionability data for your target genes and output results to CSV.

Dependency Matrix

Required Modules

None required

Components

Standard package

💻 Claude Code Installation

Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.

Please help me install this Skill:
Name: scientific-clingen-curation
Download link: https://github.com/nahisaho/satori/archive/main.zip#scientific-clingen-curation

Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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