scientific-depmap-dependencies

What problem does it solve?

Cancer research often requires integrating gene dependency and drug sensitivity data across multiple cancer cell lines, CRISPR/RNAi screens, and related metadata from the DepMap Portal. This skill provides programmatic access to the DepMap Portal API to fetch gene-dependency scores, drug sensitivity data, and gene effect metrics for downstream analysis.

Core Features & Use Cases

• Retrieve cell-line metadata, tissue types, and cancer types to contextualize dependencies.
• Fetch gene dependency scores (CRISPR/RNAi) and associated drug sensitivities for hypothesis testing and target prioritization.
• Integrate with Cell Model Passports datasets and downstream pipelines for precision oncology research.

Quick Start

Query the DepMap Portal for a given gene symbol to retrieve dependency scores and export the results for downstream analysis.