scientific-geo-expression

Search GEO datasets and retrieve expression matrices for transcriptomics analyses.

3|1|Updated Feb 11, 2026
One-click install
npx skills add https://github.com/nahisaho/satori --skill scientific-geo-expression
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: scientific-geo-expression
Source: https://github.com/nahisaho/satori/tree/main/src/.github/skills/scientific-geo-expression
Command: npx skills add https://github.com/nahisaho/satori --skill scientific-geo-expression

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Automates discovery and retrieval of GEO datasets and expression matrices to accelerate transcriptomics analyses.

Core Features & Use Cases

  • GEO dataset search (GDS/GSE) and metadata extraction
  • Expression matrix download for downstream analyses (DEG, clustering)
  • Cross-dataset comparisons and metadata-driven filtering for reproducible workflows

Quick Start

Query GEO data and fetch the corresponding expression matrix for a chosen study.

Frequently Asked Questions about scientific-geo-expression

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I download GEO expression matrices for differential expression analysis?

You can search GEO datasets (GSE or GDS) by query, organism, and study type, then retrieve the corresponding expression matrices and metadata CSVs to support downstream differential expression analysis.

Can I search GEO datasets by organism and study type?

Yes, you can search GEO datasets by specifying inputs such as organism and study type, allowing you to apply metadata-driven filtering to find relevant transcriptomics data.

What is the best way to extract RNA-seq data from GEO for cross-dataset comparisons?

The best way to extract RNA-seq data for cross-dataset comparisons is to query GEO datasets and retrieve expression matrices, applying metadata-driven filtering to align studies and support reproducible analyses.

Does this Skill support both GDS and GSE dataset formats?

Yes, the Skill supports both GDS and GSE dataset formats, allowing you to search and extract expression data across both GEO dataset types for transcriptomics analyses.

How do I handle failures when retrieving microarray expression data from GEO?

The Skill includes failure handling to support end-to-end GEO workflows, managing issues that arise when retrieving microarray expression data to ensure reproducible transcriptomics analyses.

What outputs do I get when querying GEO datasets for transcriptomics analysis?

When querying GEO datasets, the outputs include expression matrices and metadata CSVs, which provide the necessary data for downstream differential expression, clustering, and cross-dataset comparisons.