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scientific-pharmgkb-pgx

Retrieve PharmGKB drug-gene annotations, dosing guidelines, and PGx evidence.

3|1|Updated Feb 11, 2026
Search Tags:#bioinformatics#clinical-annotations#pharmacogenomics#pgx#pharmgkb#drug-gene#dosing-guidelines
One-click install
npx skills add https://github.com/nahisaho/satori --skill scientific-pharmgkb-pgx
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: scientific-pharmgkb-pgx
Source: https://github.com/nahisaho/satori/tree/main/src/.github/skills/scientific-pharmgkb-pgx
Command: npx skills add https://github.com/nahisaho/satori --skill scientific-pharmgkb-pgx

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

Retrieve pharmacogenomics evidence from PharmGKB to support clinical decision-making.

Core Features & Use Cases

  • Drug–gene search to identify relevant pharmacogenomic interactions.
  • Retrieve clinical annotations tied to genes and drugs with supporting evidence levels.
  • Discover dosing guidelines (CPIC/DPWG) and related recommendations for precision medicine.
  • End-to-end PGx interpretation and integration into downstream analyses and workflows.

Quick Start

Execute the PharmGKB PGx pipeline with a drug name and optional genes to retrieve drugs, annotations, guidelines, and gene associations.

Frequently Asked Questions about scientific-pharmgkb-pgx

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve pharmacogenomics clinical annotations from PharmGKB?▼

To retrieve pharmacogenomics clinical annotations from PharmGKB, execute the PGx pipeline with a drug name and optional genes to fetch structured annotations tied to specific drug-gene interactions with supporting evidence levels.

Can I find CPIC and DPWG dosing guidelines for drug-gene pairs?▼

Yes, you can discover CPIC and DPWG dosing guidelines by searching with a drug name, retrieving related pharmacogenomic recommendations to support clinical decision-making and precision medicine workflows.

What is the best way to integrate PharmGKB drug-gene evidence into downstream bioinformatics analyses?▼

The best way to integrate PharmGKB drug-gene evidence is using this Skill to orchestrate an end-to-end PGx pipeline, retrieving structured outputs from drug search to consolidated gene associations for seamless data integration.

Does this pharmacogenomics pipeline require external dependencies to retrieve dosing guidelines?▼

No, this pharmacogenomics pipeline operates without external dependencies, directly satisfying API access to PharmGKB for retrieving clinical annotations and dosing guidelines structured for downstream interpretation.

What limitations should I expect when searching for PGx interpretations across multiple drugs?▼

When searching for PGx interpretations across multiple drugs, the pipeline processes queries individually by drug name and optional genes, meaning the scope of clinical annotations and guidelines retrieved is constrained by available PharmGKB evidence.

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