stitch-query

Retrieve chemical–protein interactions from STITCH with resolved identifiers and scores.

130|4|Updated Mar 13, 2026

Search Tags:#knowledge-graph #interactions #stitch #protein-interactions #drug-target #stitch-api #drug-protein

Ready to run

npx skills add https://github.com/QSong-github/DrugClaw --skill stitch-query

💬 Prompt for ChatGPT / Claude Chat▼

Please help me install this Agent Skill.
Skill: stitch-query
Source: https://github.com/QSong-github/DrugClaw/tree/main/skills/dti/stitch
Command: npx skills add https://github.com/QSong-github/DrugClaw --skill stitch-query

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

STITCH provides a fast path to explore chemical–protein interactions across experimental data, databases, and text mining, enabling targeted drug-target inquiries.

Core Features & Use Cases

Auto-detects input type (CIDm/CIDs, STRING IDs, or names) and resolves to STITCH/STRING identifiers.
Retrieves interactors and actions with confidence scores for a given chemical or protein.
Returns structured results including identifiers, names, and evidence for drug–target understanding.

Quick Start

Query STITCH to fetch interactions for a given chemical or protein (e.g., imatinib) and review the returned partners.

Frequently Asked Questions about stitch-query

High-intent search queries and answers about installing and using this skill.

FAQPage Schema

How do I query chemical-protein interactions for a specific drug target?▼

To query chemical-protein interactions for a drug target, provide a chemical or protein identifier such as a CID or free-text name. The tool auto-detects the input type, resolves STITCH and STRING identifiers, and returns interactors with actions and confidence scores.

Can I retrieve STITCH interactions using a free-text chemical name instead of an ID?▼

Yes, you can retrieve STITCH interactions using a free-text chemical name instead of an ID. The query tool auto-detects free-text names alongside CIDm, CIDs, or STRING IDs, and automatically resolves them into the required STITCH identifiers to fetch interaction data.

Does querying STITCH API return confidence scores for protein interactions?▼

Querying the STITCH API does return confidence scores for protein interactions. Results include structured data detailing interactors, action mechanisms, and associated evidence scores to help evaluate the reliability of each chemical-protein interaction.

How do I filter STITCH protein interactions by species during a query?▼

You can filter STITCH protein interactions by species during a query by applying the species filtering parameter. This configuration restricts the retrieved chemical-protein interaction network to the specified organism, ensuring the structured output is relevant to your target biology.

What is the best way to limit the number of interactors returned from a STITCH query?▼

The best way to limit returned interactors from a STITCH query is by using the configurable limits parameter. This constrains the volume of chemical-protein interaction records retrieved via the REST API, keeping the structured output manageable for downstream analysis.

Are STITCH API query outputs structured for downstream drug-target analysis?▼

STITCH API query outputs are structured for downstream drug-target analysis. The tool returns formatted data containing identifiers, names, and interaction actions with scores, making the results directly suitable for integration into analytical pipelines.