tooluniverse-infectious-disease

Generate outbreak intelligence reports with taxonomy, drug targets, and docking results.

1.6k|244|Updated Mar 3, 2025
One-click install
npx skills add https://github.com/mims-harvard/ToolUniverse --skill tooluniverse-infectious-disease
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: tooluniverse-infectious-disease
Source: https://github.com/mims-harvard/ToolUniverse/tree/main/skills/tooluniverse-infectious-disease
Command: npx skills add https://github.com/mims-harvard/ToolUniverse --skill tooluniverse-infectious-disease

SYSTEM DOCUMENTATION & REQUIREMENTS

What problem does it solve?

This Infectious Disease Outbreak Intelligence Skill translates pathogen information into actionable intelligence by identifying taxonomy, essential proteins, predicting structures, and screening repurposable drugs via docking to guide rapid outbreak response.

Core Features & Use Cases

  • Pathogen profiling: Taxonomic classification, related organisms, and lineage tracking to enable knowledge transfer from well-studied pathogens.
  • Target & structure readiness: Prioritized druggable targets with predicted structures suitable for docking studies.
  • Drug repurposing & docking: Screen FDA-approved and broad-spectrum drugs against key targets to produce ranked candidates with supporting evidence.
  • Literature intelligence integration: Aggregate peer-reviewed and preprint findings to keep practitioners up-to-date during fast-moving outbreaks.

Quick Start

Use the Infectious Disease Outbreak Intelligence skill to begin with a new pathogen name (e.g., "SARS-CoV-2") and generate a complete intelligence package that includes taxonomy, drug targets, predicted structures, docking results, and literature synthesis.

Frequently Asked Questions about tooluniverse-infectious-disease

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I generate drug repurposing candidates for a novel pathogen using structure-based docking?

To generate drug repurposing candidates for a novel pathogen, provide the pathogen name to trigger taxonomic classification, essential protein prediction, and molecular docking to output ranked FDA-approved drug options with supporting evidence.

What is pathogen profiling and how does it support outbreak intelligence?

Pathogen profiling is the taxonomic classification and lineage tracking of an emerging infection. It enables knowledge transfer from well-studied related organisms to rapidly identify essential proteins and prioritize druggable targets during an urgent outbreak response.

Can I screen FDA-approved drugs against predicted protein structures of an emerging infection?

Yes, you can screen broad-spectrum and FDA-approved drugs against predicted protein structures. The skill prioritizes druggable targets suitable for docking studies and outputs ranked drug candidates with traceable sources like ChEMBL and UniProt.

How do I synthesize peer-reviewed and preprint literature for fast-moving infectious disease outbreaks?

To synthesize literature for fast-moving outbreaks, the skill integrates literature intelligence by aggregating peer-reviewed and preprint findings. This keeps practitioners up-to-date and guides urgent decision-making with traceable evidence.

Does this bioinformatics workflow integrate external databases for target prioritization?

Yes, the bioinformatics workflow integrates external data sources including NCBI Taxonomy, UniProt, ChEMBL, and NvidiaNIM to prioritize targets, predict structures, and generate actionable outbreak intelligence with traceable sources.

What is the best way to identify essential proteins and taxonomy for an unknown pathogen?

The best way to identify essential proteins and taxonomy for an unknown pathogen is inputting the pathogen name. The skill translates this into actionable intelligence by classifying taxonomy and predicting structures to guide urgent decision-making.