Artificial Intelligence for Medicine and Science @ Harvard Zitnik Lab avatar

Artificial Intelligence for Medicine and Science @ Harvard Zitnik Lab

Official

@mims-harvard · Harvard

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76Public Repos
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162Published Skills

Harvard Zitnik Lab provides a standardized framework for scientific discovery, integrating multi-omics, protein design, and clinical variant interpretation for biomedical research.

Skills Distribution
DomainAI Models & ...Biomedical Informa.. (40%)Computational Drug.. (30%)Scientific Data In.. (30%)

Agent Skills by Artificial Intelligence for Medicine and Science @ Harvard Zitnik Lab

Showing 162 vetted skills indexed across 1 GitHub repositories.

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tooluniverse-gwas-study-explorer

Compare GWAS studies, meta-analyze loci, and assess replication across cohorts.

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tooluniverse-microbiome-research

Analyze microbiome studies, taxonomic profiles, and genome quality using MGnify, GTDB, ENA, and EuropePMC.

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tooluniverse-metabolomics-analysis

Analyze metabolomics data from identification through pathway enrichment and multi-omics integration.

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tooluniverse-data-wrangling

Download and parse scientific data from APIs and file formats using Python code.

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tooluniverse-immune-repertoire-analysis

Analyzes TCR and BCR repertoire sequencing data for clonality, diversity, and antigen specificity.

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tooluniverse-single-cell

Analyze single-cell RNA-seq data with scanpy from QC gating through clustering and annotation.

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tooluniverse-admet-prediction

Profiles ADMET properties and toxicity of drug candidates from SMILES or compound names.

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tooluniverse-variant-to-mechanism

Trace genetic variants through regulatory context, target genes, and pathways to disease mechanisms.

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tooluniverse-proteomics-data-retrieval

Search and retrieve proteomics dataset metadata from MassIVE and ProteomeXchange repositories.

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tooluniverse-gpcr-structural-pharmacology

Analyzes GPCR ligands, structures, mutations, and antibody interfaces via GPCRdb, SAbDab, and PDBePISA.

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tooluniverse-meta-analysis

Pool effect sizes across multiple studies with fixed- or random-effects meta-analysis and heterogeneity statistics.

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tooluniverse-dataset-discovery

Find and evaluate research datasets across scientific repositories for any research question.

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tooluniverse-metabolomics-pathway

Maps metabolites to pathways, enzymes, genes, and disease associations across HMDB, KEGG, Reactome, and MetaCyc.

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tooluniverse-acmg-variant-classification

Classifies germline variants using ACMG/AMP criteria with evidence from ClinVar, gnomAD, and computational predictors.

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tooluniverse-epidemiological-analysis

Conducts observational epidemiology studies from PECO question to publication-ready statistical report.

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tooluniverse-structural-proteomics

Integrates PDB, AlphaFold, GPCRdb, and BindingDB data for drug target structural validation.

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tooluniverse-variant-interpretation

Classify genetic variants using ACMG guidelines with population, structural, and literature evidence.

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tooluniverse-protein-structure-prediction

Predicts protein 3D structures from sequence using ESMFold, AlphaFold, and RCSB experimental data.

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tooluniverse-microbial-genome-characterization

Discovers, quality-controls, and maps genome assemblies and replicons via NCBI Datasets.

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tooluniverse

Routes scientific data analysis questions to specialized ToolUniverse sub-skills and authoritative pipelines.

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tooluniverse-clinical-risk-scoring

Compute and interpret validated bedside clinical risk scores for individual patients.

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tooluniverse-adverse-outcome-pathway

Maps environmental chemicals to adverse outcome pathways using AOPWiki, PubChemTox, and CTD data.

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tooluniverse-spatial-transcriptomics

Analyze spatial transcriptomics data to identify tissue domains, spatially variable genes, and cell-cell interactions.

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tooluniverse-rare-disease-genomics

Investigate rare disease genetics from disease identification through variant interpretation using Orphanet, GenCC, and ClinVar.

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Frequently Asked Questions About Artificial Intelligence for Medicine and Science @ Harvard Zitnik Lab

FAQPage Schema
What specific scientific tasks can researchers perform using these resources?

Researchers can execute complex biomedical tasks including protein therapeutic design, rare disease phenotype matching, drug repurposing candidate identification, and precision oncology treatment mapping. The framework synthesizes data from public repositories like RCSB PDB, PubChem, and Open Targets to generate evidence-graded, citation-rich research reports.

Which professional personas benefit most from this research framework?

This framework is designed for computational biologists, bioinformaticians, and pharmaceutical researchers. It serves professionals focused on drug discovery, clinical genetics, and molecular medicine who require standardized, reproducible methods for retrieving and analyzing multi-omics, chemical, and clinical data at scale.

What are the prerequisites for integrating these research capabilities?

Integration requires a configured environment supporting MCP-compatible modules. Users must establish connectivity with the registry to access the underlying scientific modules, ensuring that local environments are prepared to handle structured JSON configurations and evidence-graded metadata blocks for consistent research output.