uniprot-database

UniProt REST API provides direct programmatic access to protein sequences in multiple formats including FASTA, JSON, TSV, XML, and RDF. Query by protein name, gene symbol, accession identifier, or organism; retrieve sequences and annotations through REST endpoints with field filtering and pagination support for automated workflows.

Yes, the UniProt REST API supports searches by gene name, accession number, protein name, and organism filter. Results return in your chosen format with configurable field selection, enabling batch lookups and automated protein identification across large datasets.

UniProt ID mapping via REST API converts protein identifiers between UniProt accessions and external database formats. Submit batch requests with up to 100,000 IDs; results remain accessible for 7 days, enabling large-scale cross-database reconciliation in programmatic workflows.

Query the UniProt REST API with protein accessions or search terms to retrieve GO terms, functional annotations, and structured metadata. Use field filtering to extract specific annotation types and format results as JSON, TSV, or XML for downstream analysis.

Yes, the UniProt REST API supports pagination and streaming of large datasets with batch constraints of 100,000 IDs maximum per job. Results persist for 7 days, enabling retrieval and processing of genome-scale protein collections through automated REST queries.

UniProt REST API delivers sequences and annotations in JSON, TSV, FASTA, XML, and RDF formats. Select formats based on downstream tool compatibility; use field parameters to include only required data fields and reduce response size in automated pipelines.