alterlab-depmap
CommunityIdentify cancer gene dependencies with DepMap.
AuthorAlterLab-IEU
Version1.0.0
Installs0
System Documentation
What problem does it solve?
DepMap provides a comprehensive view of gene dependencies across cancer cell lines, enabling researchers to identify potential drug targets and synthetic lethality relationships.
Core Features & Use Cases
- DepMap API access for gene dependency scores (Chronos) across hundreds of cell lines.
- Target validation, biomarker discovery, and biomarker-guided drug target identification across cancer types.
- Data integration guidance with sample_info and mutation data to correlate dependencies with genomic features.
Quick Start
Analyze a gene of interest across DepMap cell lines to identify selective dependencies and potential synthetic-lethal partners.
Dependency Matrix
Required Modules
None requiredComponents
references
💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: alterlab-depmap Download link: https://github.com/AlterLab-IEU/AlterLab-Academic-Skills/archive/main.zip#alterlab-depmap Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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