bio-clinical-databases-polygenic-risk
OfficialPredict disease risk with polygenic scores.
Authorstellaromics
Version1.0.0
Installs0
System Documentation
What problem does it solve?
Calculate polygenic risk scores from GWAS summary statistics and genotype data to predict disease susceptibility in cohorts.
Core Features & Use Cases
- Multiple methods: PRSice-2, LDpred2, and PRS-CS workflows to derive polygenic scores.
- GWAS integration: Align GWAS summary statistics with target genotypes and compute scores.
- Risk interpretation: Normalize scores, stratify into risk categories, and assess predictive performance.
Quick Start
Run a complete polygenic risk score workflow on my GWAS summary statistics and genotype data using PRSice-2, LDpred2, or PRS-CS.
Dependency Matrix
Required Modules
None requiredComponents
Standard package💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: bio-clinical-databases-polygenic-risk Download link: https://github.com/stellaromics/fast-bioinfo/archive/main.zip#bio-clinical-databases-polygenic-risk Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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