bio-crispr-screens-jacks-analysis
OfficialJoint CRISPR screen analysis for sgRNA efficacy.
Data & Analytics#data-analysis#crispr#multi-screen#jacks#screen-analysis#gene-essentiality#sgrna-efficacy
Authorstellaromics
Version1.0.0
Installs0
System Documentation
What problem does it solve?
JACKS CRISPR Screen Analysis enables joint modeling of sgRNA efficacy and gene essentiality across multiple CRISPR knockout screens, allowing researchers to decouple guide-performance from true gene effects.
Core Features & Use Cases
- Jointly analyze several CRISPR screens to learn shared sgRNA efficacy and compare gene essentiality across experiments.
- Generate gene-level essentiality scores and sgRNA-level efficacy estimates to inform library design and hit validation.
- Use across multi-condition studies to assess consistency of hits and guide performance in different cell lines or treatments.
Quick Start
Tell your AI to run JACKS on your CRISPR count data.
Dependency Matrix
Required Modules
None requiredComponents
Standard package💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: bio-crispr-screens-jacks-analysis Download link: https://github.com/stellaromics/fast-bioinfo/archive/main.zip#bio-crispr-screens-jacks-analysis Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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