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brenda-database

Retrieve enzyme kinetic parameters and reaction data from the BRENDA database via SOAP API.

8|Updated Jan 13, 2026
Search Tags:#database#drug discovery#metabolism#biochemistry#enzyme#kinetics
One-click install
npx skills add https://github.com/hxk622/TokenDance --skill brenda-database-hxk622
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: brenda-database
Source: https://github.com/hxk622/TokenDance/tree/main/backend/app/skills/builtin/scientific/chemistry/brenda-database
Command: npx skills add https://github.com/hxk622/TokenDance --skill brenda-database-hxk622

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires zeep, requests, pandas, matplotlib, seaborn, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides programmatic access to the BRENDA enzyme database, enabling researchers to quickly retrieve critical biochemical data for enzymes, saving significant time in literature review and data compilation.

Core Features & Use Cases

  • Kinetic Parameter Retrieval: Access Km, kcat, and Vmax values for enzymes across various organisms and substrates.
  • Reaction Information: Obtain detailed reaction equations, stoichiometry, and associated organisms.
  • Enzyme Discovery: Find enzymes based on substrates, products, or reaction patterns.
  • Use Case: A metabolic engineer needs to find enzymes that can convert a specific substrate into a desired product under high-temperature conditions. This Skill can query BRENDA for suitable enzymes, their kinetic properties, and optimal operating conditions.

Quick Start

Use the brenda-database skill to find kinetic parameters for enzyme 1.1.1.1 in Saccharomyces cerevisiae.

Frequently Asked Questions about brenda-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve enzyme kinetic parameters like Km and kcat from the BRENDA database?▼

You can retrieve enzyme kinetic parameters like Km and kcat from the BRENDA database by accessing the SOAP API to obtain comprehensive kinetic data, reaction equations, and organism-specific substrate information.

What is needed to access BRENDA enzyme data via SOAP API?▼

To access BRENDA enzyme data via SOAP API, you need authentication credentials and specific Python libraries including zeep, requests, pandas, matplotlib, and seaborn for SOAP communication and data parsing.

Can I find enzymes for metabolic pathway analysis based on specific substrates?▼

Yes, you can find enzymes for metabolic pathway analysis based on specific substrates by querying the BRENDA database to discover suitable enzymes, their kinetic properties, and optimal operating conditions for desired products.

Does this Skill work with pandas for analyzing biochemical reaction data?▼

Yes, this Skill works with pandas to parse and analyze biochemical reaction data, utilizing the library alongside matplotlib and seaborn to structure and visualize the retrieved enzyme kinetics and reaction equations.

What are the limitations of using BRENDA database access for enzyme discovery?▼

Limitations of using BRENDA database access include the strict requirement for authentication credentials and the necessity of specific Python libraries like zeep for SOAP communication, which adds environment setup complexity.

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