brenda-database

Accesses BRENDA enzyme database via SOAP API to retrieve kinetic parameters and metadata.

1|Updated Mar 12, 2026
One-click install
npx skills add https://github.com/yf8578/clawomics --skill brenda-database-yf8578
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: brenda-database
Source: https://github.com/yf8578/clawomics/tree/main/skills/brenda-database
Command: npx skills add https://github.com/yf8578/clawomics --skill brenda-database-yf8578

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires zeep, requests, pandas, matplotlib, seaborn, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides programmatic access to the BRENDA enzyme database, enabling researchers to quickly retrieve detailed enzyme kinetic parameters, reaction information, and organism-specific data, streamlining biochemical research and analysis.

Core Features & Use Cases

  • Kinetic Parameter Retrieval: Access Km, kcat, and Vmax values for enzymes across various organisms and substrates.
  • Reaction Information: Obtain detailed reaction equations, stoichiometry, and associated literature.
  • Enzyme Discovery: Search for enzymes based on substrates, products, or reaction patterns.
  • Organism & Environmental Data: Compare enzyme properties across species and retrieve optimal pH, temperature, and cofactor requirements.
  • Use Case: A metabolic engineer needs to find enzymes that can efficiently convert a specific substrate to a desired product under industrial conditions. This Skill can identify candidate enzymes, their kinetic properties, and optimal operating parameters.

Quick Start

Use the brenda-database skill to find enzymes that act on glucose.

Frequently Asked Questions about brenda-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve enzyme kinetic parameters like Km and kcat from the BRENDA database?

You can retrieve enzyme kinetic parameters like Km and kcat from the BRENDA database by using this Skill to access the BRENDA SOAP API, which returns structured data for specific enzymes, substrates, and organisms. It parses millions of data points for over 45,000 enzymes.

Can I search for enzymes based on specific substrates or reaction equations?

Yes, you can search for enzymes based on substrates, products, or reaction patterns. This Skill retrieves detailed reaction equations, stoichiometry, and associated literature from the BRENDA database, facilitating enzyme discovery for specific metabolic conversions.

Does the BRENDA database skill provide organism-specific environmental data like optimal pH and temperature?

Yes, the BRENDA database skill provides organism-specific environmental data including optimal pH, temperature, and cofactor requirements. This allows researchers to compare enzyme properties across species and identify candidates suitable for industrial conditions.

How do I parse and visualize BRENDA enzyme data using Python?

To parse and visualize BRENDA enzyme data, this Skill utilizes the pandas library for structuring the retrieved API data and integrates matplotlib and seaborn for generating visual plots. This enables comprehensive biochemical research and metabolic pathway analysis.

What are the limitations of using SOAP API for BRENDA database queries?

Using the SOAP API for BRENDA database queries requires valid authentication credentials and specific Python libraries like zeep for parsing XML responses. Users must handle complex query structures and parse millions of data points, which may introduce latency for large-scale retrieval.