brenda-database

Name: brenda-database
Availability: InStock
Author: OwnLab

Retrieve enzyme kinetics and reaction data from the BRENDA SOAP API.

21|1|Updated Mar 19, 2026

Search Tags:#api #data-analysis #reactions #enzyme #brenda #kinetics #km

Ready to run

npx skills add https://github.com/OwnLabAI/ownlab --skill brenda-database-ownlabai

💬 Prompt for ChatGPT / Claude Chat▼

Please help me install this Agent Skill.
Skill: brenda-database
Source: https://github.com/OwnLabAI/ownlab/tree/main/mart/skills/scientific-skills/brenda-database
Command: npx skills add https://github.com/OwnLabAI/ownlab --skill brenda-database-ownlabai

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires zeep, requests, pandas, brenda_client, and includes scripts (resource) and references (resource) components.

What problem does it solve?

Access to enzyme data is scattered; researchers spend time collecting Km, kcat, and reaction information manually from BRENDA. This skill centralizes access via SOAP API for programmatic queries.

Core Features & Use Cases

Retrieve Km values, kcat, and affinity metrics across organisms for a given EC number.
Retrieve reaction equations and substrate-specific enzyme data for pathway analysis and enzyme engineering.
Compare data across organisms and instruments to support cross-species metabolic studies.

Quick Start

Run brenda-database to fetch Km values for EC 1.1.1.1 and export results to JSON

Frequently Asked Questions about brenda-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema

How do I retrieve Km values and kcat data for a specific EC number from BRENDA?▼

Retrieve Km values and kcat data for a specific EC number by querying the BRENDA SOAP API. The skill parses and filters enzyme kinetics metrics across organisms, exporting the retrieved results to JSON for kinetic analysis.

Do I need BRENDA API credentials to programmatically access enzyme kinetics data?▼

Yes, accessing enzyme kinetics data requires valid BRENDA API credentials. The skill uses the brenda_client and network access to authenticate with the BRENDA SOAP API before retrieving reaction and affinity metrics.

Can I use pandas to export substrate-specific enzyme data for pathway reconstruction?▼

Yes, you can use pandas to export substrate-specific enzyme data for pathway reconstruction. The skill filters reaction equations by EC numbers and substrates, then structures the BRENDA API output for pandas data analysis workflows.

What is the best way to compare enzyme kinetics data across different organisms?▼

The best way to compare enzyme kinetics data across organisms is by querying the BRENDA SOAP API. This skill centralizes cross-species Km and kcat retrieval, allowing you to filter, parse, and export comparative metabolic data.

Are there limitations when using the BRENDA SOAP API for enzyme discovery?▼

Limitations of using the BRENDA SOAP API include the strict requirement for network access and valid API credentials. Additionally, the zeep-based client must parse and filter raw SOAP responses to extract clean enzyme kinetics data.

Why does querying BRENDA for enzyme kinetics require helper scripts instead of direct API calls?▼

Querying BRENDA requires helper scripts because raw SOAP API responses need structured parsing and filtering. The scripts use brenda_client and zeep to translate complex XML enzyme data into clean, exportable JSON or pandas formats.