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brenda-database

Retrieve BRENDA enzyme data via SOAP API with authentication.

15|2|Updated Dec 17, 2025
Search Tags:#brenda#soap-api#biochemical-data#enzyme-kinetics#km-values#substrate-specificity
One-click install
npx skills add https://github.com/rubensliv/k-dense-ai --skill brenda-database-rubensliv
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: brenda-database
Source: https://github.com/rubensliv/k-dense-ai/tree/main/scientific-skills/brenda-database
Command: npx skills add https://github.com/rubensliv/k-dense-ai --skill brenda-database-rubensliv

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires zeep, requests, pandas, brenda_client, and includes scripts (resource) and references (resource) components.

What problem does it solve?

Access to the BRENDA enzyme database via SOAP API is automated, enabling researchers to programmatically retrieve enzymatic data without manual lookups.

Core Features & Use Cases

  • Retrieve comprehensive kinetic data (Km, kcat) across organisms for a given EC number.
  • Retrieve reaction equations, substrate specificities, and environmental parameters to inform pathway design and enzyme engineering.
  • Compare data across organisms and substrates to identify optimal enzymes for metabolic models and retrosynthesis scenarios.

Quick Start

Query Km values for EC 1.1.1.1 across organisms to begin.

Frequently Asked Questions about brenda-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I retrieve enzyme Km values from the BRENDA database using SOAP API?▼

To retrieve enzyme Km values from the BRENDA database via SOAP API, use the brenda_client library to perform authenticated calls. You query by EC number to aggregate kinetic data across organisms.

What biochemical data can I extract using the BRENDA SOAP API?▼

The BRENDA SOAP API provides comprehensive biochemical data including Km values, kcat values, reaction equations, substrate specificities, and environmental parameters for enzyme analysis.

Do I need authentication credentials to query BRENDA enzyme data?▼

Yes, accessing BRENDA enzyme data requires authentication credentials. You must configure the brenda_client library with valid credentials to perform authenticated SOAP calls and parse responses.

Can I compare enzyme kinetics across different organisms for metabolic engineering?▼

You can compare enzyme kinetics across organisms by querying BRENDA with a specific EC number. This retrieves comparative data to identify optimal enzymes for metabolic models and pathway design.

Does the brenda-database Skill work with pandas for data aggregation?▼

Yes, the brenda-database Skill uses pandas as a dependency to parse SOAP API responses and aggregate results. This allows structured comparison of substrate specificity and kinetic data.

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