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clinpgx-database

Query pharmacogenomic data and gene–drug interactions from the ClinPGx v1 REST API.

21|1|Updated Mar 19, 2026
Search Tags:#clinical-annotations#pharmacogenomics#gene-drug#cpic#allele#clinpgx
One-click install
npx skills add https://github.com/OwnLabAI/ownlab --skill clinpgx-database-ownlabai
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: clinpgx-database
Source: https://github.com/OwnLabAI/ownlab/tree/main/mart/skills/scientific-skills/clinpgx-database
Command: npx skills add https://github.com/OwnLabAI/ownlab --skill clinpgx-database-ownlabai

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, and includes scripts (resource) and references (resource) components.

What problem does it solve?

ClinPGx provides programmatic access to consolidated pharmacogenomics data for gene–drug interactions, clinical guidelines, and variant annotations, enabling researchers and clinicians to rapidly retrieve evidence for precision medicine decisions.

Core Features & Use Cases

  • Gene & drug queries: Lookup pharmacogenes, drugs, and their interactions to support study design, dosing decisions, and safety reviews.
  • CPIC & DPWG guidelines: Retrieve guideline metadata and dosing recommendations to inform clinical decision making.
  • Allele, variant, and annotations: Access allele functions, population frequencies, and clinical annotations for pharmacogenomic interpretation.
  • Drug labels and pathways: Explore pharmacogenomic content in regulatory labels and metabolic pathways for comprehensive analyses.
  • Use case: Analyze patient PGx panels to identify high-risk genotype–drug pairs and generate report summaries.

Quick Start

Run a sample query against the ClinPGx API to fetch CPIC guidelines for CYP2C19 and clopidogrel.

Frequently Asked Questions about clinpgx-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I query pharmacogenomics data and CPIC guidelines for gene-drug interactions?▼

You query pharmacogenomics data and CPIC guidelines for gene-drug interactions by accessing the ClinPGx v1 REST API endpoint. This allows you to retrieve clinical annotations, dosing recommendations, and variant metadata for clinical decision support.

How do I retrieve CPIC dosing recommendations for specific pharmacogenes like CYP2C19?▼

Retrieve CPIC dosing recommendations for pharmacogenes like CYP2C19 by querying the ClinPGx API. It returns guideline metadata and clinical annotations supporting clinical decision making and pharmacogenomic interpretation for specific drugs.

Can I use this to analyze patient pharmacogenomics panels for high-risk genotype-drug pairs?▼

Yes, you can analyze patient pharmacogenomics panels for high-risk genotype-drug pairs. The API provides allele functions, population frequencies, and clinical annotations needed to identify risks and generate report summaries.

Does the ClinPGx API enforce rate limiting for pharmacogenomic data requests?▼

Yes, the ClinPGx API enforces rate limiting of 2 requests per second for pharmacogenomic data requests. Optional data caching is supported to manage query volume and reduce redundant API calls during panel interpretation.

What pharmacogenomic annotations are available for drug labels and metabolic pathways?▼

Available pharmacogenomic annotations for drug labels and metabolic pathways include regulatory label content and pathway mapping. You can explore this content to support study design, dosing decisions, safety reviews, and comprehensive analyses.

Do I need the requests library to access clinical annotations from ClinPGx?▼

Yes, you need the requests library to access clinical annotations from ClinPGx. It serves as the dependency for executing REST API access at the ClinPGx v1 endpoint to fetch pharmacogenomic data.

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