clinpgx-database

Query the ClinPGx API for gene-drug interactions and clinical guidelines.

Updated Aug 23, 2026
One-click install
npx skills add https://github.com/Rowtion/Bioclaw --skill clinpgx-database-rowtion
Or copy as Structured Prompt for Agent
Please help me install this Agent Skill.
Skill: clinpgx-database
Source: https://github.com/Rowtion/Bioclaw/tree/main/scientific-skills/clinpgx-database
Command: npx skills add https://github.com/Rowtion/Bioclaw --skill clinpgx-database-rowtion

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides access to comprehensive pharmacogenomics data, enabling precise, genotype-guided medication decisions and advancing precision medicine research.

Core Features & Use Cases

  • Gene-Drug Interactions: Query how genetic variations affect drug response, efficacy, and toxicity.
  • Clinical Guidelines: Access evidence-based recommendations from CPIC and other consortia.
  • Allele & Variant Data: Retrieve functional information and population frequencies for pharmacogenes.
  • Use Case: A clinician can use this Skill to quickly check if a patient's CYP2C19 genotype requires an alternative to clopidogrel, based on the latest CPIC guidelines.

Quick Start

Query the ClinPGx API for gene-drug interactions related to CYP2D6 and codeine.

Frequently Asked Questions about clinpgx-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I query pharmacogenomics gene-drug interactions for clinical dosing?

Query pharmacogenomics gene-drug interactions by accessing the ClinPGx database to retrieve genotype-guided medication data, clinical guidelines, and risk assessments for adverse drug reactions.

What pharmacogenomics guidelines are available for checking CYP2D6 and codeine interactions?

Pharmacogenomics guidelines from CPIC and other consortia are accessible programmatically, providing evidence-based recommendations for gene-drug pairs like CYP2D6 and codeine to support precision medicine.

Can I retrieve allele functional information and population frequencies for pharmacogenes?

Yes, you can retrieve allele functional information and population frequencies for pharmacogenes by querying the ClinPGx API for detailed gene-drug interaction data and variant annotations.

Does this pharmacogenomics database tool require specific dependencies to query CPIC guidelines?

Querying CPIC guidelines and pharmacogenomics data requires the Python requests library to access the ClinPGx API, enabling retrieval of clinical recommendations and allele functions.

What is the best way to access CPIC clinical guidelines for precision medicine applications?

The best way to access CPIC clinical guidelines for precision medicine is by programmatically querying the ClinPGx database, which provides structured evidence-based recommendations for genotype-guided dosing.

How do I check if a patient's CYP2C19 genotype requires a clopidogrel alternative?

Check CYP2C19 genotype interactions with clopidogrel by querying the ClinPGx database for CPIC guidelines, retrieving specific clinical recommendations for alternative medications based on genetic variations.