combination-designer
CommunityDesign rational OM drug combinations
Education & Research#drug repurposing#network pharmacology#oral mucositis#combination design#synergy assessment#Ayurvedic formulations
AuthorOpenSourcePharmaFoundation
Version1.0.0
Installs0
System Documentation
What problem does it solve?
It helps you design multi-compound treatment strategies for Oral Mucositis (OM) by evaluating synergy, pathway coverage, and cancer-therapy compatibility instead of guessing from single-agent evidence.
Core Features & Use Cases
- Rational multi-compound design: Build 2–4 component combinations that map to OM pathways and phases, including Ayurvedic multi-ingredient logic.
- Synergy and conflict assessment: Analyze target overlap, pathway convergence, sequential blockade ideas, and potential antagonistic or DDI risks (CYP, target competition, protein binding displacement).
- Formulation and safety guardrails: Check practical delivery feasibility (e.g., rinse vs gel), stability/compatibility considerations, and guard against interfering with chemotherapy.
Quick Start
Ask the AI to propose a 2–4 component combination for OM, then return a full synergy report with target overlap, pathway/phase coverage, DDI risk, formulation feasibility, and a verdict.
Dependency Matrix
Required Modules
None requiredComponents
Standard package💻 Claude Code Installation
Recommended: Let Claude install automatically. Simply copy and paste the text below to Claude Code.
Please help me install this Skill: Name: combination-designer Download link: https://github.com/OpenSourcePharmaFoundation/ospf-ayurveda-kg/archive/main.zip#combination-designer Please download this .zip file, extract it, and install it in the .claude/skills/ directory.
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