cosmic-database

Query and download somatic mutation data from the COSMIC database.

8|Updated Jan 13, 2026

Search Tags:#bioinformatics #precision oncology #cancer genomics #cosmic #mutation data #gene census

Ready to run

npx skills add https://github.com/hxk622/TokenDance --skill cosmic-database-hxk622

💬 Prompt for ChatGPT / Claude Chat▼

Please help me install this Agent Skill.
Skill: cosmic-database
Source: https://github.com/hxk622/TokenDance/tree/main/backend/app/skills/builtin/scientific/database/cosmic-database
Command: npx skills add https://github.com/hxk622/TokenDance --skill cosmic-database-hxk622

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, pandas, pysam, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill provides programmatic access to the COSMIC database, enabling researchers to query and download comprehensive cancer mutation data, gene lists, and signatures for cancer research and precision oncology.

Core Features & Use Cases

Download Mutation Data: Access somatic mutations, structural variants, and copy number alterations.
Cancer Gene Census: Retrieve curated lists of cancer-associated genes.
Mutational Signatures: Download profiles for signature analysis.
Use Case: A researcher needs to find all known oncogenes involved in lung cancer and download their associated mutation data from COSMIC to analyze mutational patterns.

Quick Start

Use the cosmic-database skill to download the Cancer Gene Census file.

Frequently Asked Questions about cosmic-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema

How do I download somatic mutation data from the COSMIC database?▼

You can download somatic mutation data from the COSMIC database by using this Skill to programmatically query and retrieve comprehensive cancer genomics datasets, including structural variants and copy number alterations for research.

Can I retrieve the Cancer Gene Census list for precision oncology applications?▼

Yes, you can retrieve the Cancer Gene Census for precision oncology applications. This Skill provides programmatic access to download curated lists of cancer-associated genes directly from the COSMIC database.

How do I access mutational signatures for cancer genomics analysis?▼

To access mutational signatures for cancer genomics analysis, use this Skill to download specific signature profiles from the COSMIC database, facilitating detailed pattern analysis for cancer research.

Do I need authentication and specific Python libraries to access COSMIC data?▼

Yes, you need authentication and specific Python libraries including requests, pandas, and pysam to access COSMIC data. These dependencies are required for data retrieval and processing within the Skill.

What is the best way to programmatically query gene fusions in the COSMIC database?▼

The best way to programmatically query gene fusions in the COSMIC database is using this Skill, which facilitates querying somatic mutations, gene fusions, and copy number alterations for cancer research.

Does this Skill support downloading copy number alterations for cancer research?▼

Yes, this Skill supports downloading copy number alterations for cancer research. It enables programmatic access to the COSMIC database to retrieve comprehensive mutation data including these specific alterations.