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cosmic-database

Download COSMIC mutation datasets, gene census, and signatures with authentication.

Updated Aug 23, 2026
Search Tags:#bioinformatics#cancer genomics#data download#cosmic#mutation data#gene census
One-click install
npx skills add https://github.com/Rowtion/Bioclaw --skill cosmic-database-rowtion
Or copy as Structured Prompt for Agent▼
Please help me install this Agent Skill.
Skill: cosmic-database
Source: https://github.com/Rowtion/Bioclaw/tree/main/scientific-skills/cosmic-database
Command: npx skills add https://github.com/Rowtion/Bioclaw --skill cosmic-database-rowtion

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill requires requests, pandas, pysam, and includes scripts (resource) and references (resource) components.

What problem does it solve?

This Skill simplifies the process of accessing and downloading critical cancer genomics data from the COSMIC database, enabling researchers to quickly obtain mutation, gene census, and signature information.

Core Features & Use Cases

  • Data Download: Programmatically download various COSMIC datasets including mutations, gene census, mutational signatures, and structural variants.
  • Authentication Handling: Manages user credentials for secure access to the database.
  • Use Case: A researcher needs to analyze somatic mutations for a specific set of cancer genes. They can use this Skill to download the relevant mutation export file and the cancer gene census list, then combine them for downstream analysis.

Quick Start

Use the cosmic-database skill to download the cancer gene census file for GRCh38.

Frequently Asked Questions about cosmic-database

High-intent search queries and answers about installing and using this skill.

FAQPage Schema
How do I download COSMIC cancer mutation data programmatically?▼

This Skill enables programmatic download of COSMIC somatic mutation data by handling user authentication and retrieving specified data types like structural variants and mutational signatures.

Does downloading COSMIC mutation data require user authentication?▼

Downloading COSMIC mutation data requires user authentication. This Skill manages your credentials to securely access and retrieve cancer genomics datasets.

Can I retrieve the Cancer Gene Census list for GRCh38 using this approach?▼

Yes, you can retrieve the Cancer Gene Census for GRCh38. This Skill facilitates downloading gene census datasets alongside somatic mutation data for cancer research.

What types of cancer genomics datasets can I access through the COSMIC database?▼

You can access comprehensive somatic mutation datasets, the Cancer Gene Census, mutational signatures, and structural variants from the COSMIC database for precision oncology research.

Do I need pysam and pandas to retrieve COSMIC data files?▼

The Skill depends on pandas and pysam, along with requests, to handle data retrieval, process cancer genomics datasets, and manage file operations for downstream bioinformatics analysis.

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