functional-genomics

Retrieve and analyze perturbation evidence from BioGRID ORCS and DepMap.

475|61|Updated May 28, 2026

Search Tags:#gene analysis #DepMap #functional genomics #perturbation evidence #BioGRID ORCS

Ready to run

npx skills add https://github.com/exon-research/genomi --skill functional-genomics

💬 Prompt for ChatGPT / Claude Chat▼

Please help me install this Agent Skill.
Skill: functional-genomics
Source: https://github.com/exon-research/genomi/tree/main/skills/functional-genomics
Command: npx skills add https://github.com/exon-research/genomi --skill functional-genomics

SYSTEM DOCUMENTATION & REQUIREMENTS

💡 This Skill includes scripts (resource) and references (resource) and assets (resource) components.

What problem does it solve?

This Skill provides access to and analysis of functional-genomics perturbation evidence, helping to understand gene interactions and their effects.

Core Features & Use Cases

Perturbation Evidence Retrieval: Fetches perturbation records from various sources, including BioGRID ORCS and DepMap.
Gene Analysis: Compares gene perturbation evidence across different experimental contexts.
Data Import: Imports local perturbation tables for analysis.
Use Case: When trying to understand the impact of a specific perturbation on a gene of interest, this skill can provide evidence-backed information from multiple sources.

Quick Start

Use the functional-genomics skill to compare gene perturbation evidence for the context 'cell line X' and perturbation 'perturbation Y'.

Frequently Asked Questions about functional-genomics

High-intent search queries and answers about installing and using this skill.

FAQPage Schema

Can I import local perturbation tables to compare with public functional genomics data?▼

Yes, you can import local perturbation tables for analysis alongside public data. The tool allows you to integrate local datasets with BioGRID ORCS and DepMap records to compare gene interaction evidence.

What is functional genomics perturbation evidence and when do I need to analyze it?▼

Functional genomics perturbation evidence consists of records showing the effects of gene interactions and disruptions. You need to analyze it when trying to understand the impact of specific perturbations on genes of interest across various experimental contexts.

Does this gene analysis approach require access to both BioGRID ORCS and DepMap?▼

Yes, retrieving and analyzing perturbation evidence requires access to both BioGRID ORCS and DepMap. These sources provide the public datasets necessary for comparing gene perturbation effects across different experimental conditions.

How do I compare gene perturbation effects across different experimental cell lines?▼

Provide a context such as a specific cell line and a target perturbation to the tool. It retrieves and compares evidence from sources like DepMap and BioGRID ORCS to analyze the impact of the perturbation on your gene of interest.