genetics-selfdecode-lookup

To lookup imputed SNP genotypes, use a tool that queries SelfDecode's imputed dataset to extend coverage beyond raw 23andMe data. It retrieves genotypes for SNPs not present in your raw file using per-SNP or batch requests.

JWT token authentication for SelfDecode lookups requires extracting a JWT from your browser session and configuring it in your profile YAML. The system validates responses and prompts for a token refresh if authentication errors occur.

Yes, you can run batch SNP queries using SelfDecode imputed data. The system efficiently fetches multiple SNPs in a single request and caches results locally for up to 30 days to accelerate subsequent genotype lookups.

The best way to check APOE variant risk is querying imputed genotypes via SelfDecode. This allows researchers to assess risk across a larger SNP set by retrieving variants like rs429358 that are missing from raw 23andMe data.

Yes, you need a SelfDecode account and its credentials configured in your profile YAML. The tool uses your account's JWT token to authenticate requests and access the imputed dataset required for specific SNP genotypes.

Your SelfDecode lookup returns an authentication error when the JWT token is expired or invalid. The system detects this failure and prompts you to refresh the JWT token from your browser session to retry the genotype query.